Included a new Annex (Annex A) providing specific examples of neutralizing agents to use during sampling to counteract disinfectants. Accessing the Full Text
Increases the probability of detecting low levels of contamination over a wide area. 🧪 The Role of Neutralizers Included a new Annex (Annex A) providing specific
For organizations looking for the official document, the verified ISO 18593:2018 PDF can be obtained directly through the or national bodies like BSI Knowledge and Afnor Editions . ISO 18593 - iTeh Standards ISO 18593 - iTeh Standards | Method |
| Method | Surface Type | Area to Sample | Verification Requirement | | :--- | :--- | :--- | :--- | | | Flat, smooth, dry surfaces (e.g., stainless steel) | 20–25 cm² | Plate must be flush with surface; no air bubbles. | | Swab Technique | Curved, irregular, hard-to-reach surfaces (pipes, crevices) | 25 cm² to 100 cm² (specified in protocol) | Use sterile templates; swab must be rotated 90° during sampling. | | Sponge Technique | Large, rough surfaces (conveyor belts, floors) | Up to 1000 cm² | Pre-moistened with neutralizing buffer. | | The standard does not apply to the
The standard does not apply to the validation of cleaning and disinfection procedures itself, nor does it cover sampling for primary production (ISO 13307), carcasses (ISO 17604), or specific viruses like Norovirus (ISO 15216-1). Key Sampling Techniques